白细胞介素-13受体a1重组兔单抗
Rrmab®兔单抗
货号：bsm-54211R
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概述
产品编号
bsm-54211R
产品类型
重组兔单抗
英文名称
IL13RA1 Recombinant Rabbit mAb
中文名称
白细胞介素-13受体a1重组兔单抗
英文别名
CD213A1; CT19; IL-13Ra; NR4; IL-13R-alpha-1; IL-13r[a]; Il13ra; I13R1_HUMAN; IL13RA1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13RA1; Cancer/testis antigen 19 (CT19); IL13R; I13R1_MOUSE; Interleukin-13-binding protein; Novel cytokine receptor 4 (NR4);
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human IL 13 receptor alpha 1: 50-101/427
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
1C1
理论分子量
47 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:500-2000 | |
| IHC-P | Human | 1:100-500 | |
| IHC-F | Human | 1:100-500 | |
| IF | Human | 1:100-500 |
交叉反应
交叉反应: Human
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靶标
基因名
IL13RA1
蛋白名
Interleukin-13 receptor subunit alpha-1
亚基
Interleukin-13 receptor is a complex of IL4R, IL13RA1, and possibly other components. Interacts with TRAF3IP1.
亚细胞定位
Membrane; Single-pass type I membrane protein.
组织特异性
Spleen, liver, thymus, heart, lung, kidney, testis, stomach, brain, skin, and colon; but not skeletal muscle.
相似性
Belongs to the type I cytokine receptor family. Type 5 subfamily.
功能
Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
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具体参考文献:bsm-54211R 被引用于2文献中
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