Rab11A Rabbit pAb (一抗) | Bioss

bs-11258R

农牧业/家禽抗体

Rab11A Rabbit pAb

G蛋白结合蛋白RAB11a抗体

Rab-11; RAB11; YL8; XELAEV_18020433mg; AB11A; rab11a; wu:fi15h09; zgc:103679; RB11A_CHICK; 3.6.5.2; RB11A_BOVIN; RB11A_CANLF; RB11A_HUMAN; RB11A_MOUSE; RB11A_PIG; RB11A_RABIT; RB11A_RAT; 24KG;

Rabbit

KLH conjugated synthetic peptide derived from human Rab11A: 141-216/216

IgG

Liquid

affinity purified by Protein A

Polyclonal

24 kDa

26 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There are over 40 Rab proteins in mammals. Rab11a and Rab11b are known markers for protein trafficking, sorting, and recycling in the endosomal pathway. The Rab11 proteins are enriched in recycling endosomes and the trans-Golgi network, where they regulate membrane recycling back to the plasma membrane. Rab11a is ubiquitously expressed, while Rab11b is expressed mainly in the heart and brain.