VMAT2 Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
VMAT2 Rabbit pAb (一抗) | Bioss
货号:bs-9565R
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概述

产品编号
bs-9565R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
VMAT2 Rabbit pAb
中文名称
脑单胺类神经递质转运蛋白抗体
英文别名
PKDYS2; SVAT; SVMT; VAT2; VMAT2; 1110037L13Rik; 9330105E13; MNAT; VMAT-2; VMAT2_HUMAN; SLC18A2; Solute carrier family 18 member 2; Vesicular amine transporter 2 (VAT2); Vesicular monoamine transporter 2; VMAT2_MOUSE; Monoamine transporter; VMAT2_RAT; solute carrier family 18 member A2; solute carrier family 18 (vesicular monoamine transporter), member 2; Synaptic vesicular amine transporter
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human VMAT2: 421-514/514
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
57 kDa
检测分子量
55 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Neurotransmission depends on the regulated exocytotic release of chemical transmitter molecules. This requires the packaging of these substances into the specialized secretory vesicles of neurons and neuroendocrine cells, a process mediated by specific vesicular transporters. The family of genes encoding the vesicular transporters of monoamines (VMAT 1 and VMAT 2) and acetylcholine (VACht) have been cloned and functionally characterized. The sequence of these integral membrane proteins predicts twelve transmembrane domains and weak homology to a class of bacterial antibiotic resistance proteins. The vesicular transport of neurotransmitter molecules has been shown to be an active ATP- and proton dependent transport mechanism.
脑单胺类神经递质转运蛋白抗体-bs-9565R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouse, RatHuman, Pig, Cow, Chicken, Dog, Horse1:500-2000

交叉反应

交叉反应: Mouse, Rat (predicted: Human, Pig, Cow, Chicken, Dog, Horse)

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靶标

基因名
SLC18A2
蛋白名
Synaptic vesicular amine transporter
亚基
Interacts with SLC6A3.
亚细胞定位
Cytoplasmic vesicle membrane.
相似性
Belongs to the major facilitator superfamily. Vesicular transporter family.
功能
Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.

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