CHRM1/M-AChR M1 Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
CHRM1/M-AChR M1 Rabbit pAb (一抗) | Bioss
货号:bs-21484R
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概述

产品编号
bs-21484R
英文名称
CHRM1/M-AChR M1 Rabbit pAb
中文名称
毒蕈碱型乙酰胆碱受体M1抗体
英文别名
HM1; M1; M1R; Chrm-1; ACM1_HUMAN; CHRM1; ACM1_MOUSE; ACM1_RAT; cholinergic receptor muscarinic 1; acetylcholine receptor, muscarinic 1
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human CHRM1/M-AChR M1: 281-380/460 <Cytoplasmic>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
51 kDa
检测分子量
51 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
AChR M1 毒蕈碱型乙酰胆碱受体M1,属于G蛋白偶联受体家族成员,主要分布于中枢神经系统和周围神经系统,乙酰胆碱与受体结合后诱导其功能:抑制酰苷酸环化酶、降解磷酸肌醇、膜钾离子通道开放.
背景资料
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008].
毒蕈碱型乙酰胆碱受体M1抗体-bs-21484R毒蕈碱型乙酰胆碱受体M1抗体-bs-21484R毒蕈碱型乙酰胆碱受体M1抗体-bs-21484R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouseHuman, Rat1:500-2000

交叉反应

交叉反应: Mouse (predicted: Human, Rat)

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靶标

基因名
CHRM1
蛋白名
Muscarinic acetylcholine receptor M1
亚基
Interacts with GPRASP2.
亚细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
相似性
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM1 sub-subfamily.
功能
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

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