Fc ε RIα/Fc epsilon RI Rabbit pAb (一抗) | Bioss
货号：bs-21972R
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概述
产品编号
bs-21972R
英文名称
Fc ε RIα/Fc epsilon RI Rabbit pAb
中文名称
FC段IgE受体α多肽/Fc ε RIα抗体
英文别名
FCE1A; FCERIA; FcERI; FCERA_HUMAN; FCER1A; Fc-epsilon RI-alpha (FcERI); IgE Fc receptor subunit alpha;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human Fc ε RIα/Fc epsilon RI: 31-130/257 <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
27 kDa
检测分子量
27 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:500-2000 |
交叉反应
交叉反应: Human
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靶标
基因名
FCER1A
蛋白名
High affinity immunoglobulin epsilon receptor subunit alpha
亚细胞定位
Cell membrane; Single-pass type I membrane protein.
相似性
Contains 2 Ig-like (immunoglobulin-like) domains.
功能
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
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