CYP2C9 Rabbit pAb (一抗) | Bioss

2026-03-02~2026-04-30,KXJ26032026-03-02~2026-04-30,促销赠品
CYP2C9 Rabbit pAb (一抗) | Bioss
货号:bs-2887R
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概述

产品编号
bs-2887R
英文名称
CYP2C9 Rabbit pAb
中文名称
细胞色素P450 2C9抗体
英文别名
CPC9; CYP2C; CYP2C10; CYPIIC9; P450-2C9; P450IIC9; CP2C9_HUMAN; CYP2C9; (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; Cholesterol 25-hydroxylase; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase; 1.14.14.1;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human CYP2C9: 351-450/490
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
56 kDa
检测分子量
52 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
细胞色素P450 2C9抗体-bs-2887R细胞色素P450 2C9抗体-bs-2887R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouseHuman, Rat1:500-2000
IHC-PMouseHuman, Rat1:200-800
IHC-FMouseHuman, Rat1:50-200
IFMouseHuman, Rat1:50-200

交叉反应

交叉反应: Mouse (predicted: Human, Rat)

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靶标

基因名
CYP2C9
蛋白名
Cytochrome P450 2C9
亚细胞定位
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
相似性
Belongs to the cytochrome P450 family.
功能
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan.

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具体参考文献:bs-2887R 被引用于6文献中

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