细胞外信号调节激酶5重组兔单抗

bsm-52069R

重组兔单抗

ERK5 Recombinant Rabbit mAb

细胞外信号调节激酶5重组兔单抗

BMK1; ERK4; ERK5; PRKM7; BMK-1; ERK-5; Erk5-T; b2b2346Clo; MK07_HUMAN; MAPK7; MAP kinase 7; MAPK 7; Big MAP kinase 1 (BMK-1); Extracellular signal-regulated kinase 5 (ERK-5); 2.7.11.24; MK07_MOUSE; MK07_RAT;

Rabbit

Recombinant human ERK5 protein, around C-terminal 200aa

IgG

Liquid

affinity purified by Protein A

Recombinant

8D8

90 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]