细胞角蛋白15重组兔单抗
Rrmab®兔单抗
货号：bsm-52055R
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概述
产品编号
bsm-52055R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
Cytokeratin 15 Recombinant Rabbit mAb
中文名称
细胞角蛋白15重组兔单抗
英文别名
CK15; K15; K1CO; Krt1-15; Ka15; K1C15_HUMAN; KRT15; Cytokeratin-15 (CK-15); Keratin-15 (K15); KRTB; K1C15_MOUSE; K1C15_RAT; Type I keratin Ka15;
抗体来源
Rabbit
免疫原
Recombinant human Cytokeratin 15 protein, around C-terminal 100aa
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
2B11
理论分子量
49 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
结构蛋白（Structural Proteins）
细胞角蛋白15对角质形成和细胞增殖活性起到一定的作用。
细胞角蛋白15对角质形成和细胞增殖活性起到一定的作用。
背景资料
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq].
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| IHC-P | Human, Mouse, Rat | 1:200-1000 | |
| IHC-F | Human, Mouse, Rat | 1:200-1000 | |
| IF | Human, Mouse, Rat | 1:200-1000 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
KRT15
蛋白名
Keratin, type I cytoskeletal 15
亚基
Heterotetramer of two type I and two type II keratins.
亚细胞定位
Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.
组织特异性
Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.
相似性
Belongs to the intermediate filament family.
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