alpha Lactalbumin Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
alpha Lactalbumin Rabbit pAb (一抗) | Bioss
货号:bs-11131R
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概述

产品编号
bs-11131R
英文名称
alpha Lactalbumin Rabbit pAb
中文名称
α-乳清蛋白抗体
英文别名
HAMLET; LYZG; LALBA_HUMAN; LALBA; Lactose synthase B protein; Lysozyme-like protein 7; LYZL7; lactalbumin alpha; lactalbumin, alpha-; lactose synthase B; lysozyme G
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human LALBA/alpha Lactalbumin: 61-142/142
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
CAS
9051-29-0
理论分子量
14 kDa
检测分子量
14 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Alpha-lactalbumin is the B protein of lactose synthetase secreted by the mammary epithelial cells. It is a potent Ca2+-elevating and apoptosis-inducing agent with broad, yet selective, cytotoxic activity. Multimeric ?lactalbumin has been shown to kill all transformed, embryonic and lymphoid cells tested, but not mature epithelial elements. This suggests that milk contributes to mucosal immunity not only by furnishing antimicrobial molecules but also by policing the function of lymphocytes and epithelium. ?lactalbumin may be helpful in discovering the site of origin of metastatic breast tumors. Human lactalbumin contains 123 amino acid residues. Comparison of the 5' flanking sequences of the two Alpha-lactalbumin genes with those of five casein genes reveals the presence of a highly conserved region extending from position -140 to -110 in all seven sequences examined, suggesting a possible regulatory role in the hormonal control or tissue-specific expression of milk protein genes in the mammary gland.
α-乳清蛋白抗体-bs-11131R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman1:500-2000

交叉反应

交叉反应: Human

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靶标

基因名
LALBA
蛋白名
alpha-lactalbumin
亚基
Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA).
亚细胞定位
Secreted.
组织特异性
Mammary gland specific. Secreted in milk.
相似性
Belongs to the glycosyl hydrolase 22 family.
功能
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.

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