5HT7 Receptor Rabbit pAb (一抗) | Bioss
货号：bs-12056R
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概述
产品编号
bs-12056R
英文名称
5HT7 Receptor Rabbit pAb
中文名称
5-羟色胺受体7抗体
英文别名
5-HT7; 5-HT-X; 5Ht7; 5HT7R_CAVPO; HTR7; 5-HT-7; Serotonin receptor 7; 5HT7R_HUMAN; 5HT7R_MOUSE; 5HT7R_RAT; GPRFO;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7: 51-150/479 <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
54 kDa
检测分子量
50 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Mouse, Rat | Human | 1:500-2000 |
| IHC-P | Human, Mouse, Rat | 1:100-500 | |
| IHC-F | Human, Mouse, Rat | 1:100-500 | |
| IF | Human, Mouse, Rat | 1:100-500 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
HTR7
蛋白名
5-hydroxytryptamine receptor 7
亚细胞定位
Cell membrane; Multi-pass membrane protein.
组织特异性
Isoform A is the predominant isoform in spleen, caudate and hippocampus.
Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression.
Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression.
相似性
Belongs to the G-protein coupled receptor 1 family.
功能
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
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