This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq, Jul 2008].
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
IHC-P
Human
1:100-500
IHC-F
Human
1:100-500
IF
Human
1:100-500
交叉反应
交叉反应: Human
相关产品
暂无相关产品
靶标
基因名
CCL1
蛋白名
C-C motif chemokine 1
亚基
Monomer.
亚细胞定位
Secreted.
相似性
Belongs to the intercrine beta (chemokine CC) family.
功能
Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.