PCDH12 Rabbit pAb (一抗) | Bioss

2026-03-02~2026-04-30,KXJ26032026-03-02~2026-04-30,促销赠品
PCDH12 Rabbit pAb (一抗) | Bioss
货号:bs-11109R
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概述

产品编号
bs-11109R
产品类型
农牧业/家禽抗体
英文名称
PCDH12 Rabbit pAb
中文名称
原钙粘附蛋白12/血管内皮钙粘蛋白2抗体
英文别名
DMJDS1; VE-cadherin-2; VECAD2; PCD12_HUMAN; PCDH12; Vascular cadherin-2; Vascular endothelial cadherin-2 (VE-cad-2 | VE-cadherin-2);
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human PCDH12: 401-500/1184 <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
126 kDa
检测分子量
126 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.
原钙粘附蛋白12/血管内皮钙粘蛋白2抗体-bs-11109R原钙粘附蛋白12/血管内皮钙粘蛋白2抗体-bs-11109R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouseHuman, Rat, Sheep, Cow, Horse1:500-2000
Flow-CytMouseHuman, Rat, Sheep, Cow, Horse1μg/Test

交叉反应

交叉反应: Mouse (predicted: Human, Rat, Sheep, Cow, Horse)

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靶标

基因名
PCDH12
蛋白名
Protocadherin-12
亚细胞定位
Cell membrane. Cell junction.
组织特异性
Expressed in highly vascularized tissues including the heart and placenta, but most tissues contain a low level of expression. Prominent expression in the spleen.
相似性
Contains 6 cadherin domains.
功能
Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Promotes homotypic calcium dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton.

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