E2F8 Rabbit pAb (一抗) | Bioss
货号：bs-4265R
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概述
产品编号
bs-4265R
产品类型
农牧业/家禽抗体
英文名称
E2F8 Rabbit pAb
中文名称
转录因子E2F8抗体
英文别名
E2F-8; 4432406C08Rik; RGD1308091; E2F8_HUMAN; E2F8; E2F8_MOUSE;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human E2F8: 265-360/968
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
94 kDa
检测分子量
93 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Cancer > Cancer Metabolism > Transcriptional control
Epigenetics and Nuclear Signaling > Transcription > Other factors
Epigenetics and Nuclear Signaling > Transcription > Transcription Factors
Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism > Molecular processes > Transcriptional control
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012].
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Rat | Human, Mouse, Rabbit, Pig, Chicken, Horse | 1:500-2000 |
| IHC-P | Mouse | Human, Rat, Rabbit, Pig, Chicken, Horse | 1:100-500 |
| IHC-F | Mouse | Human, Rat, Rabbit, Pig, Chicken, Horse | 1:100-500 |
| IF | Mouse | Human, Rat, Rabbit, Pig, Chicken, Horse | 1:100-500 |
| Flow-Cyt | Human | Mouse, Rat, Rabbit, Pig, Chicken, Horse | 1ug/Test |
交叉反应
交叉反应: Human, Mouse, Rat (predicted: Rabbit, Pig, Chicken, Horse)
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靶标
基因名
E2F8
蛋白名
Transcription factor E2F8
亚基
Forms heterodimers with E2F7 and, to a lesser extent, homodimers. Dimerization is important for DNA binding.
亚细胞定位
Nucleus.
相似性
Belongs to the E2F/DP family
功能
Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
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