This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008]
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
IHC-P
Rat
Human, Mouse, Pig, Cow, Chicken
1:100-500
IHC-F
Rat
Human, Mouse, Pig, Cow, Chicken
1:100-500
IF
Rat
Human, Mouse, Pig, Cow, Chicken
1:100-500
交叉反应
交叉反应: Rat (predicted: Human, Mouse, Pig, Cow, Chicken)
相关产品
暂无相关产品
靶标
基因名
TACR2
蛋白名
Substance-K receptor
亚细胞定位
Cell membrane; Multi-pass membrane protein.
相似性
Belongs to the G-protein coupled receptor 1 family.
功能
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.