GCNT2 Rabbit pAb (一抗) - WB | Bioss

2026-05-01~2026-06-30,AB2605
GCNT2 Rabbit pAb (一抗) - WB | Bioss
货号:bs-13316R
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概述

产品编号
bs-13316R
产品类型
农牧业/家禽抗体
英文名称
GCNT2 Rabbit pAb
中文名称
β1-6 N-乙酰氨基葡萄糖转移酶2抗体
英文别名
GNT2A_HUMAN; GCNT2; N-acetylglucosaminyltransferase; I-branching enzyme; IGNT; 2.4.1.150; GCNT5; II; NACGT1; GCNT2_MOUSE; Large I antigen-forming beta-1,6-N-acetylglucosaminyltransferase; glucosaminyl (N-acetyl) transferase 2 (I blood group); glucosaminyl (N-acetyl) transferase 5; cataract, congenital; glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group); Ii blood group; unassigned linkage group 3
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human GCNT2: 151-250/400
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
46 kDa
检测分子量
46 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Belonging to the glycosyltransferase 14 family, GCNT2 (glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)), also known as II, N-acetylglucosaminyltransferase, IGNT, CCAT, ULG3, GCNT5, GCNT2C or NACGT1, is a 400 amino acid glycosyltransferase that localizes to the Golgi apparatus. Other members of the glycosyltransferase 14 family include GCNT1, GCNT3, GCNT4, GCNT6 and GCNT7. A single-pass type II membrane protein, GCNT2 functions as a branching enzyme known as beta-1,6-N-acetylglucosaminyltransferase, which converts fetal i antigen to adult I antigen in erythrocytes during embryonic development. With expression levels increasing significantly during oncogenesis and development, GCNT2 is found at highest levels in adult prostate and fetal brain, and is found at low levels in heart, small intestine, colon, brain, pancreas and kidney.
β1-6 N-乙酰氨基葡萄糖转移酶2抗体-bs-13316R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, RatMouse, Horse1:500-2000

交叉反应

交叉反应: Human, Rat (predicted: Mouse, Horse)

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靶标

基因名
GCNT2
蛋白名
N-acetyllactosaminide beta-1, 6-N-acetylglucosaminyl-transferase
亚细胞定位
Golgi apparatus membrane.
组织特异性
In the adult, highly expressed in prostate and to a lesser extent in small intestine and colon. Barely detected in heart, brain, kidney and pancreas. No expression in placenta, lung, liver, skeletal muscle, spleen, thymus, testis, ovary and peripheral blood leukocytes. In fetus, highly expressed in brain and to a lesser extent in lung and kidney. Barely detected in liver.
相似性
Belongs to the glycosyltransferase 14 family.
功能
GCNT2 is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase that converts linear into branched poly-N-acetyllactosaminoglycans and is responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding 3 different isoforms have been described.

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