GPIHBP1 Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
GPIHBP1 Rabbit pAb (一抗) | Bioss
货号:bs-16276R
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概述

产品编号
bs-16276R
英文名称
GPIHBP1 Rabbit pAb
中文名称
高密度脂蛋白结合蛋白1抗体
英文别名
GPI-HBP1; HYPL1D; HDBP1_HUMAN; GPIHBP1; GPI-anchored HDL-binding protein 1; High density lipoprotein-binding protein 1; HBP1;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human GPIHBP1: 61-150/184
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
18 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1) is a capillary endothelial cell protein that provides a platform for LPL-mediated processing of chylomicrons. Consisting of 184 amino acids, GPIHBP1 is a single-pass membrane protein that may be regulated by dietary factors and by PPARγ. Mutations in the gene encoding GPIHBP1 are linked to chylomicronemia syndrome, a rare genetic disorder caused by LPL deficiency and is characterized by enlarged liver and spleen, inflammation of the pancreas, fatty deposits under the skin and possibly deposits in the retina of the eye.
高密度脂蛋白结合蛋白1抗体-bs-16276R

产品应用

应用已检合格种属预测种属推荐稀释比例
IHC-PHuman1:100-500
IHC-FHuman1:100-500
IFHuman1:100-500

交叉反应

交叉反应: Human

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靶标

基因名
GPIHBP1
蛋白名
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
亚基
Binds with high affinity to high-density lipoprotein (HDL) (By similarity). Binds to lipoprotein lipase (LPL), chylomicrons and APOA5.
亚细胞定位
Cell membrane. Localized at the cell surface.
翻译后修饰
Glycosylation of Asn-78 is critical for cell surface localization and the binding of chylomicrons and lipoprotein lipase (By similarity).
相似性
Contains 1 UPAR/Ly6 domain.
功能
Plays a key role in the lipolytic processing of chylomicrons.

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