SCD Rabbit pAb (一抗) - WB,IHC-P,IHC-F,IF,ELISA | Bioss
货号：bs-55193R
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概述
产品编号
bs-55193R
英文名称
SCD Rabbit pAb
中文名称
固醇酰辅酶A脱氢酶1抗体
英文别名
FADS5; MSTP008; SCD1; SCDOS; hSCD1; Scd; Scd-1; ab; SCD_HUMAN; Acyl-CoA desaturase; Delta(9)-desaturase (Delta-9 desaturase); Fatty acid desaturase; 1.14.19.1; ACOD1_MOUSE; Delta(9)-desaturase 1 (Delta-9 desaturase 1); Fatty acid desaturase 1; Stearoyl-CoA desaturase 1; ACOD1_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human SCD: 200-359/359
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
41 kDa
检测分子量
38 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins
Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Metabolism
Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Fatty acids
Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism
Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation
SWISS
Gene ID
保存条件
Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
固醇酰辅酶A脱氢酶1(SCD1)是催化细胞中饱和脂肪酸(SFA)转化为单不饱和脂肪酸(MUFA)的限速酶，在调控脂肪酸代谢、维持能量平衡、调节胰岛素敏感性及衰老等方面都发挥着重要作用，近来在肥胖、激素调节、对瘦素的作用等研究受到了重视。
背景资料
This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:500-2000 | |
| IHC-P | Human | 1:50-200 | |
| IHC-F | Human | 1:50-200 | |
| IF | Human | 1:50-200 | |
| ELISA | Human | 1:5000-10000 |
交叉反应
交叉反应: Human
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暂无相关产品
靶标
基因名
SCD
蛋白名
Stearoyl-CoA desaturase
亚细胞定位
Endoplasmic reticulum membrane; Multi-pass membrane protein (Probable).
相似性
Belongs to the fatty acid desaturase family.
功能
Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
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