PPP1R10 Rabbit pAb (一抗) - WB,IHC-P,IHC-F,IF,ICC/IF | Bioss

bs-11666R

宠物抗体、农牧业/家禽抗体

PPP1R10 Rabbit pAb

丝氨酸/苏氨酸蛋白磷酸酶1调节亚基10抗体

CAT53; FB19; PNUTS; PP1R10; R111; p99; PP1RA_HUMAN; PPP1R10; MHC class I region proline-rich protein CAT53; PP1-binding protein of 114 kDa; Phosphatase 1 nuclear targeting subunit;

Rabbit

KLH conjugated synthetic peptide derived from human PPP1R10: 151-250/940

IgG

Liquid

affinity purified by Protein A

Polyclonal

99 kDa

115 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Eukaryotic protein phosphorylation and dephosphorylation on serine and threonine residues regulates numerous cell functions, including division, homeostasis and apoptosis. A group of proteins that play a major role in this process are the serine/threonine protein phosphatases. Protein phosphatase (PP) holoenzyme is a trimeric complex that contains a regulatory subunit, a variable subunit and a catalytic subunit. Families of PP catalytic subunits include PP1, PP2A, PP2B, PP2C, PPX and PP5. Regulatory subunits include nuclear inhibitor of PP1 (NIPP1), PP1 nuclear targeting subunit (PNUTS), PP2A-A, PP2A-B, PP2A-B56, PP2A-C, PP2B-B and PR48. PNUTS, also designated CAT53 or FB19, is encoded by the gene PPP1R10. PNUTS acts as an inhibitor for the phosphatase activity of PP1 Alpha and PP1 Gamma. It is a nuclear protein primarily detected in nucleoplasmic bodies and within nucleoli. PNUTS expression levels are highest in brain, heart, lung, placenta, liver, kidney, pancreas and skeletal muscle.