Dopamine beta Hydroxylase Rabbit pAb (一抗) | Bioss
货号：bs-0596R
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概述
产品编号
bs-0596R
英文名称
Dopamine beta Hydroxylase Rabbit pAb
中文名称
多巴胺β羟化酶抗体
英文别名
DBM; ORTHYP1; DOPBHY; DOPO_BOVIN; DBH; Dopamine beta-monooxygenase; 1.14.17.1; DOPO_HUMAN; DOPO_MOUSE; DOPO_RAT; dopamine beta-hydroxylase; dopamine beta-hydroxylase (dopamine beta-monooxygenase)
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human DBH: 471-550/621
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
70 kDa
检测分子量
70 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
Dopamine-β-Hydroxylase（DBH）—多巴胺β羟化酶。可以将多巴胺转化成去甲肾上腺素。是肾上腺素能神经元的标志。
背景资料
Dopamine-beta-Hydroxylase (DBH), Dopamine can be transformed into Noradrenalin. Conversion of dopamine to noradrenaline. [SUBUNIT] Homotetramer composed of two non-covalently bound disulfide-linked dimers. [SUBCELLULAR LOCATION] Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (Potential). Belongs to the copper type II ascorbate-dependent monooxygenase family.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat | 1:500-2000 |
| IHC-P | Rat | Human, Mouse | 1:100-500 |
| IHC-F | Rat | Human, Mouse | 1:100-500 |
| IF | Rat | Human, Mouse | 1:100-500 |
| Flow-Cyt | Human | Mouse, Rat | 1ug/Test |
交叉反应
交叉反应: Human, Rat (predicted: Mouse)
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靶标
基因名
DBH
蛋白名
Dopamine beta-hydroxylase
亚基
Homotetramer composed of two non-covalently bound disulfide-linked dimers (By similarity).
亚细胞定位
Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen (By similarity).
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (By similarity).
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (By similarity).
组织特异性
Chromaffin granules of the adrenal medulla and synaptic vesicles of the sympathetic nervous system.
相似性
Belongs to the copper type II ascorbate-dependent monooxygenase family.
Contains 1 DOMON domain.
Contains 1 DOMON domain.
功能
Conversion of dopamine to noradrenaline.
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