Recombinant human CTGF protein (Active, CHO) (重组蛋白) | Bioss
货号：bs-48115P
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概述
产品编号
bs-48115P
产品类型
活性细胞因子
英文名称
Recombinant human CTGF protein (Active, CHO)
中文名称
重组人结缔组织生长因子
英文别名
CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN;
性状
Lyophilized
纯化方法
AC
理论分子量
35.5
储存液
Lyophilized from a 0.22μm-filtered solution containing PBS, 5% Mannitol, 0.01%Tween 80, pH7.4
SWISS
活性
Yes
序列
27-349/349
物种
Human
标签
Tag free
纯度
≥ 95% as determined by SDS-PAGE.
内毒素
≤10 EU/mg
表达系统
CHO cell
复溶
It is recommended to redissolve in sterile deionized water.
保存条件
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 36 months at -20℃ to -80℃ in lyophilized state. 6 months at -20℃ to -80℃ under sterile conditions after reconstitution. 7-10 days at 2℃ to 30℃ under sterile conditions after reconstitution.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
生长因子和激素（ Growth Factor and Hormones）
结缔组织生长因子（CTGF）是调节细胞增生、分化和细胞外基质形成的重要效应分子,可调节机体有关组织、细胞生长并与纤维化发生密切相关的一种因子，因而在肌体的各类创伤修复过程中具有重要的生理学意义
结缔组织生长因子（CTGF）是调节细胞增生、分化和细胞外基质形成的重要效应分子,可调节机体有关组织、细胞生长并与纤维化发生密切相关的一种因子，因而在肌体的各类创伤修复过程中具有重要的生理学意义
背景资料
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009].
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靶标
基因名
CCN2
蛋白名
CCN family member 2
亚基
Monomer.
亚细胞定位
Secreted, extracellular space, extracellular matrix. Secreted.
组织特异性
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
相似性
Belongs to the CCN family.
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 1 IGFBP N-terminal domain.
Contains 1 TSP type-1 domain.
Contains 1 VWFC domain.
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 1 IGFBP N-terminal domain.
Contains 1 TSP type-1 domain.
Contains 1 VWFC domain.
功能
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.