Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Mouse, Rat
Human
1:1000-5000
IHC-P
Human, Mouse, Rat
1:200-1000
IHC-F
Human, Mouse, Rat
1:200-1000
IF
Human, Mouse, Rat
1:200-1000
交叉反应
交叉反应: Human, Mouse, Rat
相关产品
暂无相关产品
靶标
基因名
MB
蛋白名
Myoglobin
亚细胞定位
Cytosol; Extracellular region or secreted
相似性
Belongs to the globin family.
功能
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.