半胱胺酸蛋白酶-7重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
半胱胺酸蛋白酶-7重组兔单抗
货号:bsm-63336R
产品详情
相关标记
相关产品
相关文献
常见问题

概述

产品编号
bsm-63336R
产品类型
重组兔单抗
英文名称
Caspase 7 Recombinant Rabbit mAb
中文名称
半胱胺酸蛋白酶-7重组兔单抗
英文别名
CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3; ICE-IAP3; caspase-7; mCASP-7; CASP7_MESAU; CASP7; Apoptotic protease Mch-3; ICE-like apoptotic protease 3 (ICE-LAP3); SREBP cleavage activity 2 (SCA-2); 3.4.22.60; CASP7_HUMAN; CASP7_MOUSE; Cysteine protease LICE2;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from mouse Caspase 7: 260-303/303
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
7G9
理论分子量
34 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
Caspase-7(MCH3)—属于胱氨酸-天冬氨酸蛋白酶家族,在凋亡执行阶段起中心作用。 Caspase-7受Caspase-3,-10的剪切活化,在其保守的天冬氨酸处被切成两个片段后聚合成活性酶。
背景资料
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].
半胱胺酸蛋白酶-7重组兔单抗半胱胺酸蛋白酶-7重组兔单抗半胱胺酸蛋白酶-7重组兔单抗半胱胺酸蛋白酶-7重组兔单抗半胱胺酸蛋白酶-7重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouse, Rat1:500-2000
IHC-PMouse, Rat1:100-500
IHC-FMouse, Rat1:100-500
IFMouse, Rat1:100-500

交叉反应

交叉反应: Mouse, Rat

相关产品

暂无相关产品

靶标

基因名
CASP7
蛋白名
Caspase-7
亚基
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 11 kDa (p11) subunit. Interacts with BIRC6/bruce.
亚细胞定位
Cytoplasm.
组织特异性
Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
翻译后修饰
Propeptide domains can also be cleaved efficiently by caspase-3. Active heterodimers between the small subunit of caspase-7 and the large subunit of caspase-3, and vice versa, also occur.
相似性
Belongs to the peptidase C14A family.
功能
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

标记抗体

暂无标记数据

同靶标产品

暂无同靶标产品

相关文献

提示: 发表研究结果有使用 bsm-63336R 时请让我们知道,以便我们可以引用参考文章。作为回馈,资料提供者将获得我们送上的小礼品。

暂无相关文献

常见问题

暂无常见问题