ENPP3 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss

Name: ENPP3蛋白抗体（ENPP3 Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-54812R
Availability: InStock

Rrmab^?兔单抗

2026-07-01~2026-08-31，AB2607A 京东卡2026-07-01~2026-08-31，AB2607B 豪礼卡

一键复制说明书

货号：bsm-54812R

产品详情

概述

产品编号

bsm-54812R

产品类型

重组兔单抗

英文名称

ENPP3 Recombinant Rabbit mAb

中文名称

ENPP3蛋白抗体

英文别名

B10; CD203c; NPP3; PD-IBETA; PDNP3; ENPP3_HUMAN; ENPP3; E-NPP 3; Alkaline phosphodiesterase I; Dinucleoside polyphosphatase; Nucleotide diphosphatase; Nucleotide pyrophosphatase (NPPase); Phosphodiesterase I beta (PD-Ibeta); Phosphodiesterase I/nucleotide pyrophosphatase 3; ectonucleotide pyrophosphatase/phosphodiesterase 3

抗体来源

Rabbit

免疫原

Recombinant human ENPP3 protein: 526-875/875

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

克隆号

8C6

理论分子量

100 kDa

检测分子量

140 kDa

浓度

1mg/ml

储存液

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

SWISS

O14638

Gene ID

5169

保存条件

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 5169 Human

SwissProt : O14638 Human

产品介绍

CD203c蛋白是一个糖基化的2型跨膜蛋白分子,CD203c的表达主要在嗜碱细胞、肥大细胞和它们的前体细胞上。

背景资料

The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells.

基因名

ENPP3

蛋白名

Ectonucleotide pyrophosphatase/phosphodiesterase family member 3

亚细胞定位

Membrane; Single-pass type II membrane protein (Potential). Secreted. Note=Located to the apical surface in intestinal and kidney epithelial cells. Located to the cell surface of basophils, and to the apical plasma membrane of bile duct cells. Secreted in serum, and in lumen of epithelial cells.

组织特异性

Expressed in bile ducts, prostate, uterus and colon. Exclusively expressed on basophils, mast cells and their progenitors.

翻译后修饰

N-glycosylation is necessary for correct trafficking to the apical surface, but is not the apical targeting signal.
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.

相似性

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
Contains 2 SMB (somatomedin-B) domains.

功能

Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD.