线粒体乙酰化酶3重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
线粒体乙酰化酶3重组兔单抗
货号:bsm-60944R
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概述

产品编号
bsm-60944R
产品类型
重组兔单抗
英文名称
SIRT3 Recombinant Rabbit mAb
中文名称
线粒体乙酰化酶3重组兔单抗
英文别名
SIR2L3; 2310003L23Rik; SIR3_HUMAN; SIRT3; hSIRT3; NAD-dependent protein delactylase sirtuin-3; Regulatory protein SIR2 homolog 3; SIR2-like protein 3; 2.3.1.286; SIR3_MOUSE; SIR2-like protein 3 (mSIR2L3);
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from mouse SIRT3
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
2B6
理论分子量
43 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]
线粒体乙酰化酶3重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouse1:500-2000

交叉反应

交叉反应: Mouse

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靶标

基因名
SIRT3
蛋白名
NAD-dependent protein deacetylase sirtuin-3, mitochondrial
亚基
Interacts with NDUFA9, ACSS1, IDH2 and GDH.
亚细胞定位
Mitochondrion matrix.
组织特异性
Widely expressed.
翻译后修饰
Processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product. Such processing is probably essential for its enzymatic activity.
相似性
Belongs to the sirtuin family. Contains 1 deacetylase sirtuin-type domain.
功能
NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

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