CD15/SSEA1重组兔单抗

bsm-60940R

重组兔单抗、mIHC精品抗体

CD15/SSEA1 Recombinant Rabbit mAb

CD15/SSEA1重组兔单抗

CD15; ELFT; FCT3A; FUC-TIV; FUTIV; LeX; SSEA-1; FUT4_HUMAN; FUT4; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; ELAM-1 ligand fucosyltransferase; Fucosyltransferase 4; Fucosyltransferase IV (Fuc-TIV | FucT-IV); Galactoside 3-L-fucosyltransferase;

Rabbit

IgG

Liquid

affinity purified by Protein A

Recombinant

7A9

1mg/ml

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

FUT4，也称为 ELFT 和 FCT3A，属于糖基转移酶 10 家族。FUT4 可催化参与 Lewis X/SSEA-1 和 VIM-2 抗原表达的 alpha-1,3 糖苷键。FUT4 是一种抗原表位，定义为 Lewis X 碳水化合物结构，在鼠胚胎癌细胞 (EC)、鼠 ES 和 iPS 细胞以及鼠和人类生殖细胞上表达。它被广泛用作小鼠未分化 ES 和 iPS 细胞的阳性表面标志物和人未分化 ES 和 iPS 细胞的阴性表面标志物。

The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq].