FC段γ受体3/免疫球蛋白G Fc段受体III重组兔单抗

bsm-54679R

重组兔单抗、mIHC精品抗体

CD16 Recombinant Rabbit mAb

FC段γ受体3/免疫球蛋白G Fc段受体III重组兔单抗

CD16; CD16-II; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; FcGRIIIA; IGFR3; IMD20; CD16-2; Fcgr4; FCG3A_HUMAN; FCGR3A; IgG Fc receptor III-A; CD16a antigen; Fc-gamma RIII-alpha (Fc-gamma RIII | Fc-gamma RIIIa | FcRIII | FcRIIIa | FcgammaRIIIA); IgG Fc receptor III-2; FCGR3_MOUSE; IgG Fc receptor III; Fc-gamma RIII (FcRIII); FCGR3_RAT;

Rabbit

A synthesized peptide derived from human CD16: 191-254

IgG

Liquid

affinity purified by Protein A

Recombinant

9F8

27 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]