c20orf72 Rabbit pAb (一抗) | Bioss

2026-05-01~2026-06-30,AB2605
c20orf72 Rabbit pAb (一抗) | Bioss
货号:bs-15115R
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概述

产品编号
bs-15115R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
c20orf72 Rabbit pAb
中文名称
20号染色体开放阅读框72抗体
英文别名
C20orf72; DDK1; MTDPS11; bA504H3.4; MGME1_HUMAN; MGME1; 3.1.-.-; mitochondrial genome maintenance exonuclease 1; chromosome 20 open reading frame 72
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human c20orf72: 201-300/344
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
39 kDa
检测分子量
39 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf72 gene product has been provisionally designated C20orf72 pending further characterization.
20号染色体开放阅读框72抗体-bs-15115R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHumanMouse, Rat, Rabbit, Sheep, Cow, Chicken, Dog, Horse1:500-2000

交叉反应

交叉反应: Human (predicted: Mouse, Rat, Rabbit, Sheep, Cow, Chicken, Dog, Horse)

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靶标

基因名
MGME1
蛋白名
Mitochondrial genome maintenance exonuclease 1
亚细胞定位
Mitochondrion.
疾病
Note=Defects in MGME1 are a cause of cause of progressive external ophthalmoplegia with mitochondrial DNA deletions (PEOAX). progressive external ophthalmoplegia with mitochondrial DNA deletions is characterized by external ophthalmoplegia, emaciation and respiratory failure. Muscle biopsies show mtDNA depletion and multiple mtDNA deletions.
相似性
Belongs to the MGME1 family.
功能
Single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair.

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