InChi Key
InChIKey=YYDUWLSETXNJJT-MTJSOVHGSA-N
Smiles
Cc1c(cc(cc1)NC(=O)Nc1c(ccc(c1)C(F)(F)F)F)Nc1cc2c(cc1)/C(=C/c1ccc[nH]1)/C(=O)N2
作用靶点
c-Kit; PDGFR; Trk receptor
溶解性
Soluble in DMSO、Ethanol
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).