Versican Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF | Bioss

bsm-63236R

重组兔单抗

Versican Recombinant Rabbit mAb

蛋白聚糖Versican重组兔单抗

CSPG2; ERVR; GHAP; PG-M; WGN; WGN1; 5430420N07Rik; 9430051N09; DPEAAE; NG2; PG-M(V0); PG-M(V1); hdf; CSPG2_HUMAN; VCAN; Chondroitin sulfate proteoglycan core protein 2 (Chondroitin sulfate proteoglycan 2); Glial hyaluronate-binding protein (GHAP); Large fibroblast proteoglycan; CSPG2_MOUSE; CSPG2_RAT; versican; chondroitin sulfate proteoglycan 2; versican proteoglycan

Rabbit

A synthesized peptide derived from human VCAN: 3200-3280

IgG

Liquid

affinity purified by Protein A

Recombinant

12F7

373 kDa

373 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.

VCAN

Versican core protein

Interacts with FBLN1 (By similarity).

Secreted, extracellular space, extracellular matrix.

Cerebral white matter and plasma. Isoform V0 and isoform V1 are expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas. Isoform V2 is restricted to normal brain and gliomas. Isoform V3 is found in all these tissues except medulloblastomas.

Phosphorylation sites are present in the extracellular medium.

Defects in VCAN are the cause of Wagner syndrome type 1 (WGN1) [MIM:143200]. WGN is a dominantly inherited vitreoretinopathy characterized by an optically empty vitreous cavity with fibrillary condensations and a preretinal avascular membrane. Other optical features include progressive chorioretinal atrophy, perivascular sheating, subcapsular cataract and myopia. Systemic manifestations are absent in WGN.

Belongs to the aggrecan/versican proteoglycan family.
Contains 1 C-type lectin domain.
Contains 2 EGF-like domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Contains 2 Link domains.
Contains 1 Sushi (CCP/SCR) domain.

May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.