核基质蛋白3重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
核基质蛋白3重组兔单抗
货号:bsm-63230R
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概述

产品编号
bsm-63230R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
MATR3 Recombinant Rabbit mAb
中文名称
核基质蛋白3重组兔单抗
英文别名
ALS21; MPD2; VCPDM; 1110061A14Rik; 2810017I02Rik; D030046F20Rik; mKIAA0723; P130/MAT3; snhg4; MATR3_HUMAN; MATR3; KIAA0723; MATR3_MOUSE; MATR3_RAT; Nuclear scaffold protein p130/MAT3;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Matrin 3: 750-800/847
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
5F9
理论分子量
95 kDa
检测分子量
125 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.
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产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
IHC-PHuman, Mouse, Rat1:50-200
IHC-FHuman, Mouse, Rat1:50-200
IFHuman, Mouse, Rat1:50-200
Flow-CytHumanMouse, Rat1:50-100
ICC/IFHumanMouse, Rat1:50-200

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
MATR3
蛋白名
Matrin-3
亚基
Part of complex consisting of SFPQ, NONO and MATR3. Interacts with EIF2C1 and EIF2C2.
亚细胞定位
Nucleus matrix.
疾病
Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders.
相似性
Contains 1 matrin-type zinc finger.
Contains 2 RRM (RNA recognition motif) domains.
功能
May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.

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