MATR3 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss
Rrmab?兔单抗
货号：bsm-63230R
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概述
产品编号
bsm-63230R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
MATR3 Recombinant Rabbit mAb
中文名称
核基质蛋白3重组兔单抗
英文别名
ALS21; MPD2; VCPDM; 1110061A14Rik; 2810017I02Rik; D030046F20Rik; mKIAA0723; P130/MAT3; snhg4; MATR3_HUMAN; MATR3; KIAA0723; MATR3_MOUSE; MATR3_RAT; Nuclear scaffold protein p130/MAT3; matrin 3; myopathy, distal 2
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Matrin 3: 750-800/847
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
5F9
理论分子量
95 kDa
检测分子量
125 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.
基因名
MATR3
蛋白名
Matrin-3
亚基
Part of complex consisting of SFPQ, NONO and MATR3. Interacts with EIF2C1 and EIF2C2.
亚细胞定位
Nucleus matrix.
疾病
Defects in MATR3 are the cause of myopathy distal type 2 (MPD2) [MIM:606070]; also called vocal cord and pharyngeal dysfunction with distal myopathy (VCPDM). MPD2 is a muscular disorder characterized by distal weakness, with onset in hands and feet, associated with vocal cord and pharyngeal weakness causing a nasal voice and swallowing disorders.
相似性
Contains 1 matrin-type zinc finger.
Contains 2 RRM (RNA recognition motif) domains.
Contains 2 RRM (RNA recognition motif) domains.
功能
May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human, Mouse, Rat | 1:50-200 | |
| IHC-F | Human, Mouse, Rat | 1:50-200 | |
| IF | Human, Mouse, Rat | 1:50-200 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
| ICC/IF | Human | Mouse, Rat | 1:50-200 |
交叉反应
交叉反应: Human, Mouse, Rat
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