phospho-SMAD1/5/9 (S463/S465/S467) Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt | Bioss

Rrmab?兔单抗
2026-03-02~2026-04-30,KXJ2603
phospho-SMAD1/5/9 (S463/S465/S467) Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt | Bioss
货号:bsm-63164R
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概述

产品编号
bsm-63164R
产品类型
磷酸化抗体、重组兔单抗
英文名称
phospho-SMAD1/5/9 (S463/S465/S467) Recombinant Rabbit mAb
中文名称
磷酸化SMAD1/5/9 (S463/S465/S467)重组兔单抗
英文别名
SMAD1 & SMAD5 & SMAD9 (phospho-S463/S465/S467); p-SMAD1 & SMAD5 & SMAD9; phospho-SMAD1 & SMAD5 & SMAD9; SMAD1 & SMAD5 & SMAD9 (phospho-Ser463/Ser465/Ser467); DWFC; JV5-1; MADH5; 1110051M15Rik; Dwf-C; MusMLP; SMAD5_HUMAN; SMAD5; MAD homolog 5; Mothers against DPP homolog 5; SMAD family member 5 (SMAD 5 | Smad5 | hSmad5); SMAD5_MOUSE; Dwarfin-C (Dwf-C); SMAD family member 5 (SMAD 5 | Smad5 | mSmad5); Msmad5; SMAD5_RAT; SMAD family member 5 (SMAD 5 | Smad5);
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human SMAD1 around the phosphorylation site of S463 and S465: PIS-pS-V-pS
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
4F9
理论分子量
52 kDa
检测分子量
52 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.
磷酸化SMAD1/5/9 (S463/S465/S467)重组兔单抗-bsm-63164R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
Flow-CytHumanMouse, Rat1:50-100

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
SMAD5
蛋白名
Mothers against decapentaplegic homolog 5
亚基
May form trimers with the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit and SMURF1. Interacts with SUV39H1 and SUV39H2. Interacts (via MH2 domain) with LEMD3. Interacts with WWP1.
亚细胞定位
Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
组织特异性
Ubiquitous.
翻译后修饰
Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase.
Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1.
相似性
Belongs to the dwarfin/SMAD family.
Contains 1 MH1 (MAD homology 1) domain.
Contains 1 MH2 (MAD homology 2) domain.
功能
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).

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