肿瘤相关钙信号传感器2重组兔单抗
Rrmab®兔单抗
货号：bsm-43037R
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概述
产品编号
bsm-43037R
产品类型
重组兔单抗、病理级抗体、mIHC精品抗体
英文名称
TROP2 Recombinant Rabbit mAb
中文名称
肿瘤相关钙信号传感器2重组兔单抗
英文别名
EGP-1; EGP1; GA733-1; GA7331; GP50; M1S1; TROP2; Ly97; Prp1; TACD2_HUMAN; TACSTD2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1; TACD2_MOUSE; TACD2_RAT; Parturition-related protein 1;
抗体来源
Rabbit
免疫原
Recombinant human TROP2 protein
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
6F1
理论分子量
33 kDa
浓度
1mg/ml
储存液
10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| IHC-P | Human | 1:100-500 | |
| IHC-F | Human | 1:100-500 | |
| IF | Human | 1:100-500 |
交叉反应
交叉反应: Human
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靶标
基因名
TACSTD2
蛋白名
Tumor-associated calcium signal transducer 2
亚细胞定位
Membrane; Single-pass type I membrane protein.
组织特异性
Placenta, pancreatic carcinoma cell lines.
翻译后修饰
The N-terminus is blocked.
疾病
Corneal dystrophy, gelatinous drop-like (GDLD) [MIM:204870]: A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity. Note=The disease is caused by mutations affecting the gene represented in this entry.
相似性
Belongs to the EPCAM family.
Contains 1 thyroglobulin type-1 domain.
Contains 1 thyroglobulin type-1 domain.
功能
May function as a growth factor receptor.
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