A-Raf重组兔单抗

bsm-52015R

重组兔单抗

A-RAF Recombinant Rabbit mAb

A-Raf重组兔单抗

A-RAF; ARAF1; PKS2; RAFA1; sb:eu994; wu:fk45h07; zgc:92074; ARAF_HUMAN; ARAF; Proto-oncogene A-Raf; Proto-oncogene A-Raf-1; Proto-oncogene Pks; 2.7.11.1; PKS; ARAF_PIG; ARAF_RAT;

Rabbit

Recombinant human A-RAF protein (150-300aa)

IgG

Liquid

affinity purified by Protein A

Recombinant

24D1

68 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.