Recombinant human AMH protein, C-His (重组蛋白) | Bioss
货号：bs-42006P
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概述
产品编号
bs-42006P
英文名称
Recombinant human AMH protein, C-His
中文名称
重组人Muellerian缪勒管激素抑制因子蛋白
英文别名
MIS_HUMAN; Anti muellerian hormone; MIF; MIS; Muellerian inhibiting factor; Mullerian inhibiting substance; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance; Recombinant human AMH protein, C-His
性状
Lyophilized or Liquid
纯化方法
AC
理论分子量
17.2
检测分子量
20 kDa
浓度
＞0.5 mg/ml
储存液
4M Urea (pH9.0) with 1mM DDT.
研究领域
活性
Not tested
序列
453-560/560
标签
C-His
纯度
>90% as determined by SDS-PAGE
内毒素
Not analyzed
表达系统
E.coli
复溶
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
保存条件
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008].
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靶标
基因名
AMH
蛋白名
Muellerian-inhibiting factor
亚基
Homodimer; disulfide-linked.
亚细胞定位
Secreted.
疾病
Persistent Muellerian duct syndrome 1 (PMDS1) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Note=The disease is caused by mutations affecting the gene represented in this entry.
相似性
Belongs to the TGF-beta family.
功能
This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.