CALR | Calreticulin Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss
Rrmab?兔单抗
货号：bsm-52436R
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概述
产品编号
bsm-52436R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
CALR | Calreticulin Recombinant Rabbit mAb
中文名称
钙网蛋白重组兔单抗
英文别名
CALR1; CRT; HEL-S-99n; RO; SSA; cC1qR; Calregulin; CALR_HUMAN; CALR; CRP55; Endoplasmic reticulum resident protein 60 (ERp60); HACBP; grp60; CRTC; CALR_MOUSE; CALR_RAT; CALBP; Calcium-binding protein 3 (CABP3); calreticulin; Sicca syndrome antigen A (autoantigen Ro; calreticulin); autoantigen Ro
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Calreticulin: 45-86/417
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
3D1
理论分子量
44 kDa
检测分子量
55 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]
基因名
CALR
蛋白名
Calreticulin
亚基
Monomer. Component of an EIF2 complex at least composed of CELF1/CUGBP1, CALR, CALR3, EIF2S1, EIF2S2, HSP90B1 and HSPA5. Interacts with PDIA3/ERp57 (By similarity). Interacts with NR3C1 and TRIM21. Interacts with GABARAP.
亚细胞定位
Endoplasmic reticulum lumen. Cytoplasm, cytosol. Secreted, extracellular space, extracellular matrix. Cell surface.
相似性
Belongs to the calreticulin family.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:2000-10000 | |
| IHC-P | Human, Mouse, Rat | 1:200-800 | |
| IHC-F | Human, Mouse, Rat | 1:200-800 | |
| IF | Human, Mouse, Rat | 1:200-800 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
| ICC/IF | Human | Mouse, Rat | 1:100-200 |
交叉反应
交叉反应: Human, Mouse, Rat
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具体参考文献:bsm-52436R 被引用于12文献中