CD40 重组兔单克隆抗体

bsm-60748R

重组兔单抗、KO/KD Validated

CD40 Recombinant Rabbit mAb

CD40 重组兔单克隆抗体

Bp50; CDW40; TNFRSF5; p50; GP39; HIGM1; IGM; IMD3; T-BAM; TRAP; TNR5_HUMAN; CD40; B-cell surface antigen CD40; CD40L receptor; TNR5_MOUSE;

Rabbit

KLH conjugated synthetic peptide derived from human CD40

IgG

Liquid

affinity purified by Protein A

Recombinant

4F9

30 kDa

44-50 kDa

1mg/ml

PBS, Glycerol, BSA.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Predicted to enable antigen binding activity; protein domain specific binding activity; and ubiquitin protein ligase binding activity. Involved in B cell mediated immunity; CD40 signaling pathway; and cellular calcium ion homeostasis. Acts upstream of or within several processes, including defense response to other organism; positive regulation of B cell activation; and positive regulation of interleukin-12 production. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Part of CD40 receptor complex. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule). [provided by Alliance of Genome Resources, Apr 2022]