Cyclophilin B Mouse mAb, Loading Control (一抗) - WB,IHC-P,IHC-F,IF | Bioss

Cyclophilin B Mouse mAb, Loading Control (一抗) - WB,IHC-P,IHC-F,IF | Bioss
货号:bsm-33228M
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概述

产品编号
bsm-33228M
产品类型
内参抗体、胞质(包浆或全细胞)内参抗体
英文名称
Cyclophilin B Mouse mAb, Loading Control
中文名称
亲环蛋白PPIB(内参)单克隆抗体
英文别名
CYP-S1; CYPB; HEL-S-39; OI9; SCYLP; Cphn-2; Cphn2; CyP-20b; PPIB_HUMAN; PPIB; PPIase B; Cyclophilin B; Rotamase B; S-cyclophilin (SCYLP); 5.2.1.8; PPIB_MOUSE; PPIB_RAT; peptidylprolyl isomerase B; peptidyl-prolyl cis-trans isomerase B; S-cyclophilin
抗体来源
Mouse
免疫原
KLH conjugated synthetic peptide derived from human Cyclophilin B
亚型
IgG
性状
Size : 50ul/100ul/200ul
Liquid

Size : 200ug (PBS only)
Lyophilized
Note: Centrifuge tubes before opening. Reconstitute the lyophilized product in distilled water. Optimal concentration should be determined by the end user.
纯化方法
affinity purified by Protein G
克隆类型
Monoclonal
克隆号
4C7
理论分子量
20 kDa
检测分子量
20 kDa
浓度
1mg/ml
储存液
Size : 50ul/100ul/200ul
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Size : 200ug (PBS only)
0.01M PBS
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
The cyclophilins are a conserved class of proteins that bind the immunosuppressive drug cyclosporin A (CsA) with high affinity. CsA blocks helper T-cell activation at a step between T-cell receptor stimulation and the transcriptional activation of cytokine genes. Cyclophilins from many species possess peptidyl-prolyl cis-trans isomerase (PPIase) activity that is blocked by CsA and therefore may be relevant in CsA-mediated immunosuppression.
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产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
IHC-PHuman, Mouse, Rat1:100-500
IHC-FHuman, Mouse, Rat1:100-500
IFHuman, Mouse, Rat1:100-500

交叉反应

交叉反应: Human, Mouse, Rat

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暂无相关产品

靶标

基因名
PPIB
蛋白名
Peptidyl-prolyl cis-trans isomerase B
亚细胞定位
Endoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
疾病
Defects in PPIB are the cause of osteogenesis imperfect ype 9 (OI9) [MIM:259440]. OI9 is a connective tissue disorder characterized by bone fragility, low bone mass and bowing of limbs due to multiple fractures. Short limb dwarfism and blue sclerae are observed in some but not all patients.
相似性
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
Contains 1 PPIase cyclophilin-type domain.
功能
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

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