等电压依赖性阴离子通道（内参）重组兔单抗

bsm-52251R

内参抗体、重组兔单抗、线粒体蛋白内参抗体、离子通道抗体、mIHC精品抗体

VDAC1 Recombinant Rabbit mAb, Mitochondrial Loading Control

等电压依赖性阴离子通道（内参）重组兔单抗

PORIN; VDAC-1; Vdac5; mVDAC1; mVDAC5; fa13f11; wu:fa13f11; zgc:85830;

Rabbit

A synthesized peptide derived from human VDAC1: 1-66

IgG

Liquid

affinity purified by Protein A

Recombinant

9A7

32 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

电压依赖性阴离子通道VDAC是存在于线粒体外膜上的31kDa蛋白,能在膜上形成亲水性通道,调控阴离子、阳离子、ATP以及其他代谢物进出线粒体,在调节细胞代谢、维持胞内钙稳态,调节细胞凋亡和坏死等过程中发挥重要功能。

Voltage dependent anion selective channel protein 1 (VDAC/Porin) belongs to the eukaryotic mitochondrial porin family and forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation selective. VDAC/Porin expression is observed in the heart,liver and skeletal muscle.