ASH1L Antibody Blocking Peptide (合成多肽) | Bioss

货号:bs-11866P
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概述

产品编号
bs-11866P
英文名称
ASH1L Antibody Blocking Peptide
中文名称
KMT2H蛋白封闭多肽
英文别名
KMT2H / ASH1; KMT2H; ASH1; Absent small and homeotic disks protein 1 homolog; Absent Small or Homeotic Like; ASH 1 ; ASH 1L; ash1 (absent small or homeotic 1); Ash1 (absent small or homeotic) like ; ASH1-like protein; ASH1L; ASH1L_HUMAN; ASH1L1; FLJ10504; huASH1; KIAA1420; Lysine N-methyltransferase 2H; Probable histone-lysine N-methyltransferase ASH1L.
纯化方法
HPLC
活性
Not tested
保存条件
Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.

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靶标

基因名
ASH1L
蛋白名
Histone-lysine N-methyltransferase ASH1L
亚细胞定位
Nucleus. Cell junction, tight junction. Chromosome (Probable). Note=The relevance of tight junction localization is however unclear.
组织特异性
Widely expressed, with highest level in brain, heart and kidney.
相似性
Belongs to the histone-lysine methyltransferase family. SET2 subfamily.
Contains 3 A.T hook DNA-binding domains.
Contains 1 AWS domain.
Contains 1 BAH domain.
Contains 1 bromo domain.
Contains 1 PHD-type zinc finger.
Contains 1 post-SET domain.
Contains 1 SET domain.
功能
Histone methyltransferase. Probably methylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation.

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