CLTC Antibody Blocking Peptide (合成多肽) | Bioss

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货号：bs-2932P
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概述

产品编号
bs-2932P
英文名称
CLTC Antibody Blocking Peptide
中文名称
网格蛋白重链封闭多肽
英文别名
CHC17; Clathrin heavy chain 1; Clathrin heavy chain 2; Clathrin heavy chain; Clathrin heavy chain like 1; Clathrin heavy chain on chromosome 17; Clathrin heavy polypeptide; CLH 17; CLH 22; CLH-17; CLH1_HUMAN; CLH17; CLH22; CLTC; CLTCL; CLTCL1; CLTCL2; CLTD; Hc; KIAA0034.
纯化方法
HPLC
研究领域

Signal Transduction > Protein Trafficking > Vesicle Transport > Coat Proteins

Tags & Cell Markers > Subcellular Markers > Organelles > Caveolae and Clathrin

活性
Not tested
保存条件
Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接

Entrez Gene : 1213 Human

Entrez Gene : 67300 Mouse

Entrez Gene : 54241 Rat

Omim : 118955 Human

SwissProt : Q00610 Human

SwissProt : Q68FD5 Mouse

SwissProt : P11442 Rat

Unigene : 491351 Human

Unigene : 479526 Mouse

Unigene : 3589 Rat

背景资料
Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. [provided by RefSeq, Jul 2008].

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靶标

基因名
CLTC
蛋白名
Clathrin heavy chain 1
亚基
Clathrin triskelions, composed of 3 heavy chains and 3 light chains, are the basic subunits of the clathrin coat. In the presence of light chains, hub assembly is influenced by both the pH and the concentration of calcium. Interacts with HIP1. Interacts with DENND1A, DENND1B and DENND1C (By similarity). May interact with OCRL. Interacts with ERBB2 (By similarity).
亚细胞定位
Cytoplasmic vesicle membrane. Membrane > coated pit. Melanosome. Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
相似性
Belongs to the clathrin heavy chain family.
Contains 7 CHCR (clathrin heavy-chain) repeats.
功能
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.

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