Neurexin 2 Rabbit pAb (一抗) | Bioss
货号：bs-21901R
产品详情
相关标记
相关产品
相关文献
常见问题
概述
产品编号
bs-21901R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
Neurexin 2 Rabbit pAb
中文名称
轴突蛋白2抗体
英文别名
6430591O13Rik; mKIAA0921; NRX2A_HUMAN; NRXN2; Neurexin II-alpha; Neurexin-2-alpha; KIAA0921; NRX2A_RAT; neurexin 2; neurexin II
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human Neurexin 2: 231-330/1712 <Extracellular>
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
182 kDa
检测分子量
35 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).[provided by RefSeq, Jun 2010]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat, Dog, Horse | 1:500-2000 |
交叉反应
交叉反应: Human (predicted: Mouse, Rat, Dog, Horse)
相关产品
暂无相关产品
靶标
基因名
NRXN2
蛋白名
Neurexin-2
亚基
The laminin G-like domain 1 binds to NXPH1. Specific isoforms bind to alpha-dystroglycan. Interacts with INADL.
亚细胞定位
Membrane; single-pass type I membrane protein.
组织特异性
Predominantly expressed in brain.
相似性
Belongs to the neurexin family.
Contains 3 EGF-like domains.
Contains 6 laminin G-like domains.
Contains 3 EGF-like domains.
Contains 6 laminin G-like domains.
功能
Neurexin 2 alpha belongs to the Neurexin family, a group of neuronal proteins that function as cell adhesion molecules during synaptogenesis and intracellular signaling. Mammalian genomes contain just three neurexin genes. However, many neurexin isoforms may be expressed through the use of two alternative promoters and alternative splicing at up to five different positions.
同靶标产品
相关文献
提示: 发表研究结果有使用 bs-21901R 时请让我们知道，以便我们可以引用参考文章。作为回馈，资料提供者将获得我们送上的小礼品。