DLL1 Rabbit pAb (一抗) | Bioss

2026-03-02~2026-04-30,KXJ26032026-03-02~2026-04-30,促销赠品
DLL1 Rabbit pAb (一抗) | Bioss
货号:bs-21906R
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概述

产品编号
bs-21906R
产品类型
宠物抗体、农牧业/家禽抗体
英文名称
DLL1 Rabbit pAb
中文名称
Notch信号通路Delta样配体1抗体
英文别名
DELTA1; DL1; Delta; NEDBAS; DLL1_HUMAN; DLL1; Drosophila Delta homolog 1 (Delta1 | H-Delta-1); DLL1_MOUSE; Drosophila Delta homolog 1 (Delta1); DLL1_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human DLL1: 111-210/723
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
76 kDa
检测分子量
76 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Notch proteins have been found to be overexpressed or rearranged in human tumors. Ligands for Notch include Jagged, Jagged-2 and Delta. While blocking the differentiation of progenitor cells into the B cell lineage, Delta promotes the emergence of a population of cells with T cell/NK-cell characteristics. Delta is a membrane protein expressed in heart, pancreas, brain and muscle during gastrulation and early organogenesis, and in adult heart and lung.
Notch信号通路Delta样配体1抗体-bs-21906RNotch信号通路Delta样配体1抗体-bs-21906R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouseHuman, Rat, Rabbit, Sheep, Cow, Chicken, Dog1:500-2000

交叉反应

交叉反应: Mouse (predicted: Human, Rat, Rabbit, Sheep, Cow, Chicken, Dog)

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靶标

基因名
DLL1
蛋白名
delta-like protein 1
亚基
Interacts with Notch receptors.
亚细胞定位
Membrane.
组织特异性
Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.
翻译后修饰
Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
相似性
Contains 1 DSL domain.
Contains 8 EGF-like domains.
功能
Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

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