Histone H1.0 Rabbit pAb (一抗) - WB,IHC-P,IHC-F,IF,ELISA | Bioss
货号：bs-33535R
产品详情
相关标记
相关产品
相关文献
常见问题
概述
产品编号
bs-33535R
英文名称
Histone H1.0 Rabbit pAb
中文名称
组蛋白H1.0抗体
英文别名
H1.0; H10; H1F0; H1FV; D130017D06Rik; H1(0); H1-0; H10_HUMAN; Histone H1'; Histone H1(0); H10_MOUSE; MyD196; H10_RAT;
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human Histone H1.0: 51-150/194
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
21 kDa
检测分子量
32 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human, Mouse, Rat | 1:100-500 | |
| IHC-F | Human, Mouse, Rat | 1:100-500 | |
| IF | Human, Mouse, Rat | 1:100-500 | |
| ELISA | Human, Mouse, Rat | 1:5000-10000 |
交叉反应
交叉反应: Human, Mouse, Rat
相关产品
暂无相关产品
靶标
基因名
H1-0
蛋白名
Histone H1.0
亚细胞定位
Cytoplasm. Nucleus. Chromosome.
组织特异性
Oocyte-specific.
翻译后修饰
Phosphorylated on Ser-17 in RNA edited version.
相似性
Belongs to the histone H1/H5 family.
Contains 1 H15 (linker histone H1/H5 globular) domain.
Contains 1 H15 (linker histone H1/H5 globular) domain.
功能
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
同靶标产品
相关文献
提示: 发表研究结果有使用 bs-33535R 时请让我们知道，以便我们可以引用参考文章。作为回馈，资料提供者将获得我们送上的小礼品。