P选择素/白细胞内皮细胞粘附分子3重组兔单抗

bsm-60008R

重组兔单抗

CD62p Recombinant Rabbit mAb

P选择素/白细胞内皮细胞粘附分子3重组兔单抗

CD62; CD62P; GMP140; GRMP; LECAM3; PADGEM; PSEL; GMP-140; LYAM3_HUMAN; SELP; CD62 antigen-like family member P; Granule membrane protein 140 (GMP-140); Leukocyte-endothelial cell adhesion molecule 3 (LECAM3); Platelet activation dependent granule-external membrane protein (PADGEM); GMRP; LYAM3_MOUSE;

Rabbit

A synthesized peptide derived from human CD62P: 800-830

IgG/Kappa

Liquid

affinity purified by Protein A

Recombinant

20C16

88 kDa

140/90 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

P-选择素(P—selectin)是细胞黏附分子选择素家族的主要成员，又称CD62p，可以介导各种白细胞和肿瘤细胞的粘附。
CD62p又称GMP—140或PADGEM蛋白(血小板活化依赖α颗粒膜蛋白),它在血小板与单核细胞及中性粒细胞相互作用中起关键作用。

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]