真核启动因子2α(eIFα2)兔单克隆抗体

bsm-60003R

重组兔单抗、mIHC精品抗体

EIF2S1 Recombinant Rabbit mAb

真核启动因子2α(eIFα2)兔单克隆抗体

IF2A_HUMAN; EIF2S1; Eukaryotic translation initiation factor 2 subunit alpha (eIF-2-alpha | eIF-2A | eIF-2alpha | eIF2-alpha); EIF2A; IF2A_MOUSE; IF2A_RAT;

Rabbit

KLH conjugated synthetic peptide derived from human EIF2S1

IgG

Liquid

affinity purified by Protein A

Recombinant

5A1

36 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

eIF2α（真核启动因子2α）

eIF2 alpha is a 36 kDa protein which is ubiquitously expressed in many cell types. The eIF2 protein, which is composed of three subunits (alpha, beta and gamma), is one of the key molecules in the initiation of translation. In mammalian cells, eIF2 alpha is phosphorylated at serine 51 (human EIF2 alpha, the equivalent residue in mouse is serine 52) by at least two kinases: the haem-controlled repressor (HCR) and the interferon inducible double stranded RNA-dependent protein kinase (PKR). Phosphorylation of eIF2 alpha blocks the GDP-GTP exchange activity of eIF2 beta, resulting in the suppression of protein synthesis. The phosphorylation of eIF2 alpha is an important regulatory process in protein synthesis.