Azurocidin/HBP Mouse mAb (一抗) - WB,IHC-P,IHC-F,IF,ELISA | Bioss
货号：bsm-41704M
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概述
产品编号
bsm-41704M
产品类型
mIHC精品抗体
英文名称
Azurocidin/HBP Mouse mAb
中文名称
天青素/肝素结合蛋白单克隆抗体
英文别名
AZAMP; AZU; CAP37; HBP; HUMAZUR; NAZC; hHBP; CAP7_HUMAN; AZU1; Cationic antimicrobial protein CAP37; Heparin-binding protein (HBP | hHBP);
抗体来源
Mouse
免疫原
Recombinant Human Azurocidin Protein: 20-250/251
亚型
IgG1
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Monoclonal
克隆号
5F1
理论分子量
24 kDa
检测分子量
38-42 kDa
储存液
0.01M PBS (pH7.4).
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:500-2000 | |
| IHC-P | Human | 1:100-500 | |
| IHC-F | Human | 1:100-500 | |
| IF | Human | 1:100-500 | |
| ELISA | Human | 1:5000-10000 |
交叉反应
交叉反应: Human
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靶标
基因名
AZU1
蛋白名
Azurocidin
亚基
Monomer.
亚细胞定位
Cytoplasmic granule. Note=Cytoplasmic granules of neutrophils.
Belongs to the peptidase S1 family. Elastase subfamily.
Contains 1 peptidase S1 domain.
Belongs to the peptidase S1 family. Elastase subfamily.
Contains 1 peptidase S1 domain.
相似性
Belongs to the peptidase S1 family. Elastase subfamily.
Contains 1 peptidase S1 domain.
Contains 1 peptidase S1 domain.
功能
This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.
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