细胞表面趋化因子受体7重组兔单抗

bsm-52774R

重组兔单抗

CCR7 Recombinant Rabbit mAb

细胞表面趋化因子受体7重组兔单抗

BLR2; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1; Ebi1h; CCR7_HUMAN; CCR7; C-C CKR-7; Epstein-Barr virus-induced G-protein coupled receptor 1 (EBI1 | EBV-induced G-protein coupled receptor 1); MIP-3 beta receptor; EVI1; CCR7_MOUSE;

Rabbit

A synthesized peptide derived from human CCR7: 1-62

IgG

Liquid

affinity purified by Protein A

Recombinant

8C1

42 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

趋化因子是当今细胞因子研究领域的热点之一,它参与多种免疫及炎症反应,在感染、肿瘤的生长与转移、组织修复及创伤愈合等病理生理过程中发挥重要作用.CCR7在肿瘤的生长与转移方面起到一定的作用.

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq, Jul 2008]