三磷酸腺苷结合转运蛋白G超家族成员2重组兔单抗

bsm-52821R

重组兔单抗

ABCG2 Recombinant Rabbit mAb

三磷酸腺苷结合转运蛋白G超家族成员2重组兔单抗

ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; CDw388; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1; ABCG2; ABCG2_HUMAN; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; Urate exporter; 7.6.2.2; ABCG2_MOUSE; Breast cancer resistance protein 1 homolog; ABCG2_PIG; Brain multidrug resistance protein; ABCG2_RAT;

Rabbit

A synthesized peptide derived from human ABCG2: 150-200/655

IgG

Liquid

affinity purified by Protein A

Recombinant

4C4

72 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Hematopoietic/Neural Stem Cell Marker （造血/神经干细胞标志物)

An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.