高密度脂蛋白受体/清道夫受体重组兔单抗

bsm-52283R

重组兔单抗

SCARB1/Scavenger Receptor BI Recombinant Rabbit mAb

高密度脂蛋白受体/清道夫受体重组兔单抗

CD36L1; CLA-1; CLA1; HDLCQ6; HDLQTL6; SR-BI; SRB1; AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII; 9330185J12Rik; LIMP II; MLGP85; CD36; Chohd1; D5Ertd460e; Hdlq1; Hlb398; SR-B1; SRBI; mSR-BI; SCRB2_HUMAN; SCARB2; 85 kDa lysosomal membrane sialoglycoprotein (LGP85); CD36 antigen-like 2; Lysosome membrane protein II (LIMP II); Scavenger receptor class B member 2; LIMP2; SCRB1_HUMAN; SCARB1; CD36 and LIMPII analogous 1 (CLA-1); CD36 antigen-like 1; Collagen type I receptor, thrombospondin receptor-like 1; SCRB2_MOUSE; SCRB1_MOUSE; SCRB2_RAT; SCRB1_RAT;

Rabbit

KLH conjugated synthetic peptide derived from human SCARB1/Scavenger Receptor BI

IgG

Liquid

affinity purified by Protein A

Recombinant

1C2

61 kDa

1mg/ml

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

组织细胞中存在多种高密度脂蛋白受体或高密度脂蛋白结合蛋白，这些受体蛋白的组成、结构及一般特征各不相同；高密度脂蛋白受体在脂质代谢中发挥着重要的作用。

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI (Scavenger Receptor BI) protein binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland. Scavenging Receptor SR-BI plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer.