Thrombospondin 2 Rabbit pAb (一抗) | Bioss
货号：bs-7524R
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概述
产品编号
bs-7524R
产品类型
农牧业/家禽抗体
英文名称
Thrombospondin 2 Rabbit pAb
中文名称
血小板反应蛋白2/凝血酶敏感蛋白2抗体
英文别名
EDSCLL3; TSP2; Thbs-2; TSP-2; TSP2_CHICK; THBS2; TSP2_BOVIN; Corticotropin-induced secreted protein (CISP); TSP2_HUMAN; TSP2_MOUSE; thrombospondin 2
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human Thrombospondin 2: 201-300/1172
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
128 kDa
检测分子量
128 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
SWISS
Gene ID
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat, Horse | 1:500-2000 |
交叉反应
交叉反应: Human (predicted: Mouse, Rat, Horse)
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靶标
基因名
THBS2
蛋白名
Thrombospondin-2
亚基
Homotrimer; disulfide-linked. Interacts (via the TSP type I repeats) with CD36; the interaction conveys an antiangiogenic effect. Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS2 with CD36. Can bind to fibrinogen, fibronectin, laminin and type V collagen.
组织特异性
High expression in invertebral disk tissue.
疾病
Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD) [MIM:603932]; also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain.
相似性
Belongs to the thrombospondin family.
Contains 2 EGF-like domains.
Contains 1 laminin G-like domain.
Contains 1 TSP C-terminal (TSPC) domain.
Contains 3 TSP type-1 domains.
Contains 8 TSP type-3 repeats.
Contains 1 VWFC domain.
Contains 2 EGF-like domains.
Contains 1 laminin G-like domain.
Contains 1 TSP C-terminal (TSPC) domain.
Contains 3 TSP type-1 domains.
Contains 8 TSP type-3 repeats.
Contains 1 VWFC domain.
功能
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.
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